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. 2018 Dec 20;3(24):e124912. doi: 10.1172/jci.insight.124912

Figure 5. Glucose tolerance at follow-up in the adult cohort.

Figure 5

(A) Plasma glucose concentrations during a 75-g OGTT at baseline (dotted lines) and follow-up (full lines) in insulin hypersecretors (HyperS, n = 313) and normosecretors (NormS, n = 640) in the RISC study cohort. Follow-up plasma glucose levels were analyzed by repeated-measure ANOVA including group (HyperS vs. NormS), time, and group × time interaction as factors, followed by post hoc pairwise comparisons using Tukey HSD tests. Plots are mean ± SD. (B) Incidence of dysglycemia at follow-up (progressors) in HyperS and NormS in the RISC study cohort. Asterisks denote values that are significantly (*P ≤ 0.05) different between HyperS and NormS.