Table 1.
RS-S Control (n = 19) | RS-S chABC (n = 35) | p-Value | RS-D Control (n = 8) | RS-D chABC (n = 13) | p-Value | Burst Control (n = 6) | Burst chABC (n = 6) | p-Value | |
---|---|---|---|---|---|---|---|---|---|
RMP (mV) | −68.9 ± 8.2 | −69.2 ± 7.85 | 0.81 | −69.8 ± 4.2 | −66.6 ± 5.9 | 0.32 | −70.0 ± 5.8 | −63.05 ± 5.8 | 0.13 |
Spike delay (ms) | 0.087 ± 0.05 | 0.085 ± 0.1 | 0.62 | 0.007 ± 0.003 | 0.009 ± 0.16 | 0.52 | 0.006 ± 0.0019 | 0.004 ± 0.003 | 0.29 |
Rin (MΩ) | 0.15 ± 0.06 | 0.14 ± 0.05 | 0.79 | 0.16 ± 0.08 | 0.13 ± 0.05 | 0.55 | 0.19 ± 0.04 | 0.17 ± 0.04 | 0.31 |
Sag Ratio | 0.99 ± 0.05 | 0.98 ± 0.05 | 0.074 | 0.96 ± 0.02 | 0.96 ± 0.02 | 0.96 | 0.94 ± 0.02 | 0.91 ± 0.02 | 0.18 |
Threshold (mV) | −39.06 ± 8.1 | −39.4 ± 75 | 0.75 | −37.9 ± 5.7 | −42.9 ± 12.4 | 0.43 | 81.78 ± 10.1 | 71.79 ± 6.8 | 0.065 |
Half width (ms) | 1.87 ± 0.52 | 1.83 ± 0.32 | 0.29 | 1.24 ± 0.24 | 1.47 ± 0.32 | 0.08 | 1.56 ± 0.76 | 1.25 ± 0.4 | 0.23 |
Rise slope (mV/ms) | 154.4 ± 47.9 | 163.9 ± 35.8 | 0.91 | 145.6 ± 28.5 | 165.2 ± 71.5 | 0.89 | 131.0 ± 35.0 | 106.2 ± 26.5 | 0.69 |
Decay slope (mV/ms) | −33.0 ± 9.0 | −30.1 ± 9.5 | 0.92 | −48.34 ± 10.9 | −37.71 ± 9.42 | 0.053 | −46.14 ± 8.3 | −37.41 ± 12.9 | 0.39 |
AP Amplitude (mV) | 93.9 ±11.6 | 94.1 ± 5.9 | 0.64 | 74.62 ± 11.59 | 89.42 ± 17.5 | 0.25 | 81.78 ± 10.1 | 71.79 ± 6.8 | 0.065 |
AHP (mV) | −43.0 ± 8.9 | −41.8 ± 9.6 | 0.78 | −42.72 ± 4.27 | −41.04 ± 11.75 | 0.21 | −44.0 ±11.9 | −27.92 ± 17.4 | 0.11 |
dV/dT ratio | 0.23 ± 0.04 | 0.24 ± 0.04 | 0.22 | 0.35 ± 0.02 | 0.30 ± 0.15 | 0.38 | 0.35 ± 0.03 | 0.40 ± 0.03 | 0.19 |
Maximum AP Frequency (Hz) | 17.0 ± 1.4 | 16.1 ± 5 | 0.55 | 24.5 ± 8.5 | 24.0 ± 16.5 | 0.37 | 33.0 ± 23.8 | 26.5 ± 3.3 | 0.47 |
Interspike intervals (ms) | 0.48 ± 0.23 | 0.45 ± 0.12 | 0.82 | 0.14 ± 0.11 | 0.19 ± 0.11 | 0.52 | 0.11 ± 0.66 | 0.16 ± 0.66 | 0.38 |