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Comparative delivery of doxorubicin into HT-29 tumor spheroids by THZN, NTHZN nanoplatforms versus free doxorubicin (at identical initial drug dose of 5 µg/mL), revealed via a) confocal fluorescence microscopy, showing spheroid image and fluorescence signal in cross section and b) quantified by fluorescence spectroscopy, post spheroid digestion.
