Table 1. Aspirational but feasible goals for control and elimination of HIV incidence and HIV-related mortality based on existing methods.

Control
	HIV Transmission	HIV Mortality
Modes of Transmission	Sexual Injection drug use	N/A—recommend goal of elimination (rather than control) for HIV mortality
Tools	PrEP Condom use VMMC HIV testing Couples counseling and testing ARV treatment and viral suppression Needle exchange programs Opioid substitution programs
Barriers	Stigma Behavior change Silent infections Insufficient resources
Elimination
	HIV Transmission	HIV Mortality
Modes of Transmission	Mother-to-child Blood transfusion associated	N/A
Tools	Prenatal HIV testing ARV therapy Safe baby formula Blood supply HIV testing	HIV testing ARV therapy
Barriers	Awareness Resources Lack of availability of safe alternatives to breastfeeding in some populations	Stigma Resources Adherence Complementary services needed to support adherence and treat comorbid conditions such as substance abuse, tuberculosis, and hepatitis
Comments	Uniquely feasible opportunities to completely eliminate HIV incidence attributable to these two modes of transmission	N/A

Abbreviations: ARV, antiretroviral; N/A, nonapplicable; PrEP, pre-exposure prophylaxis; VMMC, voluntary medical male circumcision.