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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Neuroimage. 2018 Nov 17;186:446–454. doi: 10.1016/j.neuroimage.2018.11.019

FIGURE 2.

FIGURE 2

Distributional Transformation: Panel A shows the uncertainty in transforming Aβ-PET data with unknown distributional proportions. With low/high burden proportions creating an uncertainty envelope in the mid range. (Panel B) Raw Aβ-PET values from PiB and FBP show significant differences in their distributions. (Panel C) After linear scaling distributional differences remain. (Panel D) After NoDiM transformation Aβ-PET distributions can be aligned closely, maximizing the probability of transformed burdens aligning.