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. Author manuscript; available in PMC: 2020 Jan 17.
Published in final edited form as: Cell Chem Biol. 2018 Oct 25;26(1):27–34.e4. doi: 10.1016/j.chembiol.2018.10.003

Table 1.

Inhibition of different gut bacteria by compounds secreted by C. difficile ATCC 9689, C. scindens ATCC 35704, and C. sordellii ATCC 9714

Test bacteria strains Cell growth of bacteria(O.D at 600nm) in PYF for 24hr
C.diffiicle ATCC 9689 C.scindens ATCC 35704 C.sordellii ATCC 9714 Staph.aureus (MRSA) Ent.faecium ATCC 2316 E.coli ATCC 2340 B.vulgatus ATCC 8482
0.81 0.78 0.85 0.58 0.69 0.71 0.98
C.scindens ATCC 35704 spent culture medium UN 0.54±0.07* 0.31±0.11** 0.34±0.23* 0.30±0.01** 0.41±0.03* 0.47±0.04*
IN 0.26±0.05** 0.10±0.02** 0.08±0.03** 0.25±0.03** 0.38±0.04* 0.24±0.11**
C.sordellii ATCC 9714 spent culture medium UN 0.08±0.01** 0.08±0.01** 0.08±0.03** 0.10±0.02** 0.07±0.03** 0.10±0.03**
C.difficile ATCC 9689 spent culture medium - 0.12±0.04** 0.32±0.03** 0.24±0.14* 0.33±0.05** 0.28±0.03** 0.53±0.05*

: No addition of CA,

: Induced by 100μM CA.

*, **

: Significant growth inhibition p<0.05 and p< 0.01, respectively.