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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Neurochem Int. 2018 Sep 1;123:13–21. doi: 10.1016/j.neuint.2018.08.015

Table 3:

Bmax and Kd values for CFT binding determined for DAT in various cell lines.

Cell Lines CFT Bmax
(fmol/mg)
CFT Kd
(nM)
Reference
rDAT
LLC-PK1 681 - 804a 32 - 77 (Moritz et al., 2013)
COS-7 7000 4 - 22 (Eshleman et al., 1995; Kitayama et al., 1992)
hDAT
LLC-PK1 2000 ± 200 22 ± 3 (Zhen and Reith, 2016)
CHO hDAT 5 – 10b 8 - 9 (Midde et al., 2015; Slusher et al., 1997)
HEK 1000 – 13,000 16 - 22 (Berfield et al., 1999; Chen et al., 2000; Wang et al., 2003; Zhen et al., 2015,2005)
N2a 2500 ± 300 19 - 22 (Little et al., 2002; Zhang et al., 1998)
SK-N-MC - 18 ± 4 (Sweeney et al., 2017)
a

fmol/well

b

pmol/105 cells