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. Author manuscript; available in PMC: 2020 Jan 17.
Published in final edited form as: Cell Chem Biol. 2018 Nov 1;26(1):35–47.e7. doi: 10.1016/j.chembiol.2018.10.005

Table 1:

Catalytic rate constants and efficiencies of the QStE and QSE substrates for the indicated depalmitoylating enzymes.

Enzyme Substrate km (μM) kcat (s−1) kcat/km (s−1M−1)
TgPPT1 QStE
QSE
5.7±1.5
42.6±5.6
(1.7±0.1) × 10−2
(1.6±0.1) × 10−2
3,000
380
HsAPT1 QStE
QSE
14.5±2.8
19.1 ±5.7
(4.6±0.4) × 10−2
(0.3±0.1) × 10−2
3,200
160
HsAPT2 QStE
QSE
19.3±3.2
37.5±15.2
(4.4±0.3) × 10−2
(0.26±0.06) × 10−2
2,300
69