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. 2018 Dec 27;30(4):635–649. doi: 10.1089/ars.2017.7350

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© James M. Phang, 2017; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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FIG. 5. — Pathways activated by MYC and PI3K. Enzymes or pathways upregulated by MYC and PI3K are shown in red. Abbreviations are as shown in figures 1–3. NAD, total nicotinamide adenine dinucleotide; NADP, total nicotinamide adenine dinucleotide phosphate; NAM, nicotinamide; NAMPT, nicotinamide phosphoryl transferase; NMN, nicotinamide mononucleotide; OxPPP, oxidative arm of pentose phosphate pathway; PRPP, phosphoribosyl pyrophosphate; R-5-P, ribose-5-phosphate; SIRT1, sirtuin 1.