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. 2018 Oct 23;33(2):3024–3034. doi: 10.1096/fj.201801002R

Figure 5 .


Figure 5

Generation of conditional smooth muscle–specific BDNF knockout mice. BDNFfl/fl/SMMHC11Cre/0 and BDNFfl/fl/SMMHC110/0 were generated for the present studies. A) Wild-type (437 bp), BDNFfl/fl (487 bp), BDNFfl/0 (437 and 487 bp), and SMMHC11Cre/0 (287 bp) genotypes were assessed by PCR. B) BDNFfl/fl/SMMHC110/0 treated with 1 mg 4OHTM for 5 consecutive days led to deletion of BDNF in airway smooth muscle (identified by α-smooth muscle actin). Original magnification, ×400.