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Signs/Symptoms Warranting Immediate Referral
| Pain of unknown etiology |
| Weakness, numbness, tingling in the extremities |
| Change in balance or coordination |
| Change in vision |
| Change in intensity or frequency of headaches |
| Neurofibromas that change rapidly in size and/or color, or cause pain |
| Abnormal neurologic exam |
| Sudden onset of hypertension |
| Regression of cognitive skills or loss of developmental milestones |
| Significant deviation from individual’s established pattern of growth |
