Table 1.

Exogenous RNaseH1 overexpression reduces cell-killing activity of FG but not FA

Compound	IC50, μM*
	U2OS	U2OS_RH	U2OS_RH + Doxy
FG	15.9 ± 1.2	52.8 ± 1.1	92.8 ± 1.1
FA	6.77 ± 1.4	7.10 ± 1.3	7.12 ± 1.3
PDS	>50	>50	>50

^*Compound concentration inhibiting 50% of cell growth (see SI Appendix, Methods). Cells were exposed to the indicated compound for 24 h, and cell survival was determined after a further 48 h in drug-free medium. Numbers are means ± SD of two biological replicates, each performed in triplicate.