Table 7.
Accuracy of diagnostic tools for strongyloidiasis at different pre-test prevalence levels, 2012–February 2017.
| Index tests | True-Positives Pre-Test Probability a |
False-Positives Pre-Test Probability a |
True-Negatives Pre-Test Probability a |
False-Negatives Pre-Test Probability a |
% Infected Correctly Diagnosed | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Test % Prevalence b | 2.5% | 10% | 30% | 2.5% | 10% | 30% | 2.5% | 10% | 30% | 2.5% | 10% | 30% | |
| Baermann method [51] | 18 | 72 | 216 | 0 | 0 | 0 | 975 | 900 | 700 | 7 | 28 | 84 | 72% |
| Agar plate [51] | 22 | 89 | 267 | 0 | 0 | 0 | 975 | 900 | 700 | 3 | 11 | 33 | 89% |
| NIE-LIPS [62] | 21 | 85 | 255 | 49 | 45 | 35 | 926 | 855 | 665 | 4 | 15 | 45 | 85.1% |
| IVD-ELISA (commercial test) [62] | 23 | 92 | 276 | 29 | 27 | 21 | 946 | 873 | 679 | 2 | 8 | 24 | 92% |
| IFAT [62] | 23 | 94 | 282 | 127 | 117 | 91 | 848 | 783 | 609 | 2 | 6 | 18 | 93.8% |
| Bordier-ELISA (commercial kit) [62] | 23 | 91 | 272 | 58 | 54 | 42 | 917 | 846 | 658 | 2 | 9 | 28 | 90.7% |
| SS-NIE-1 ELISA [63] | 24 | 95 | 285 | 68 | 63 | 49 | 907 | 837 | 651 | 1 | 5 | 15 | 95% |
ELISA: enzyme-linked immunosorbent assay; IFAT: indirect fluorescent antibody technique; IVD: Invitro diagnostic test; LIPS: luciferase immunoprecipitation system; NIE: 31-kDa recombinant antigen from St. stercoralis.
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a Data reported as effect per 1000 migrants tested.
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b pre-test prevalence or probability of having schistosomiasis in an at-risk population.