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. Author manuscript; available in PMC: 2019 Jan 19.
Published in final edited form as: Chem Rev. 2018 Jun 22;118(14):6573–6655. doi: 10.1021/acs.chemrev.8b00031

Figure 68.

Figure 68.

Sequence alignment of human P450 17A1 and zebrafish P450s 17A1 and 17A2. Arg-358 (K-helix) in human P450 17A1 and zebrafish P450 17A2 and Cys-369 (K-helix) are marked. The gene nomenclature corresponding to the human and zebrafish P450s is indicated in the last section of the sequences. Red amino acids are identical and blue vary between the sequences.