Table 4.

Uni- and multivariable analysis of RFS and OAS for various high risk subgroups of pN1-patients stratified by LN ratio for pN1-patients with 10 ≤ or more than 10 LN excised

Number of excised LN	LN ratio	univariate	multivariatea
≤10	RFS	P < 0.001; HR = 5,47; (95% CI 2,30-13,4)	P < 0.001; HR = 5,34; (95% CI 2,24-12,70)
	OAS	P < 0.001; HR = 4,30; (95% CI 2,28-8,10)	P = 0.001; HR = 2,99; (95% CI 1,50-5,56)
> 10	RFS	P < 0.001; HR = 6,45; (95% CI 4,74-8,78)	P < 0.001; HR = 4,57; (95% CI 3,29-6,36)
	OAS	P < 0.001; HR = 6,29; (95% CI 4,77-8,30)	P < 0.001; HR = 3,40; (95% CI 2,53-4,56)

Uni- and multivariate analysis of RFS and OAS stratified by LN ratio (as continuous variable) for pN1-patients with 10 and less LN versus more than 10 LN excised; ^aadjusted by age, tumor size, intrinsic sub types and guideline adherent adjuvant systemic therapy