Figure 2.
Normalized Spinal Cord Cross-sectional Area by Prenatal Treatment.
Serial sections at the MMC defect epicenter for each lamb were imaged and the cross-sectional spinal cord area measured and normalized to the cross-sectional area for the corresponding lumbar level of normal lambs. Lambs that were repaired with Medium density PMSC-ECM had significantly higher spinal cord cross-sectional areas (0.90 ± 0.14% of normal) when compared to lambs that received Low density PMSC-ECM (0.43 ± 0.26% of normal) or the ECM vehicle alone (0.47 ± 0.28% of normal).