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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Eur Urol. 2018 Nov 7;75(2):242–250. doi: 10.1016/j.eururo.2018.10.040

Fig. 1.

Fig. 1

A whole-genome CRISPR screen to identify mediators of cisplatin resistance in a bladder cancer cell line. (A) Experimental outline of the screen and analysis. (B) A heatmap displaying median-centered counts for 9757 differentially abundant sgRNAs. (c) Counts from the screen for the top 10 resistant sgRNAs. (D) A volcano plot displaying the log2 fold change and adjusted p value for all sgRNAs identified in the screen. A threshold of adjusted p < 0.05 is indicated in the plot.