Table 2.
Primary and secondary outcome measures after 3 and 9 months of intervention: ITT analyses
| Outcome variable | All (N = 123) | HT (N = 45) | TM (N = 37) | PMR (N = 41) | Difference versus baseline (p) | Difference between interventions (p) |
|---|---|---|---|---|---|---|
| Number of days with headache per 4 weeks (mean ± SD) | ||||||
| Baseline | 18.9 (9.5) | 18.2 (9.6) | 20.1 (9.0) | 18.5 (9.8) | – | 0.64b |
| 3 months | 12.5 (8.8) | 12.1 (9.4) | 13.2 (9.6) | 12.3 (7.6) | < 0.001 a | 0.85b |
| 9 months | 10.5 (9.0) | 9.8 (9.8) | 11.8 (9.1) | 10.0 (7.9) | < 0.001 a | 0.57b |
| ≥ 50% reduction in headache frequency (%) | ||||||
| Baseline | – | – | – | – | – | – |
| 3 months | 50 (41%) | 20 (44%) | 15 (41%) | 15 (37%) | – | 0.76c |
| 9 months | 58 (47%) | 24 (53%) | 17 (46%) | 17 (42%) | 0.17d | 0.54c |
aPaired t test
bOne-sided ANOVA
cChi-squared test
dMcNemar test
Italicized p-values indicate a statistically significant difference