Table 4.
Parameters | NTR | HTR | Nif. 10 | L h 100 | L h 200 |
---|---|---|---|---|---|
ALT (U/L) | 22.84 ± 1.29 | 30.56 ± 2.242 | 15.71 ± 0.95c2 | 17.90 ± 0.62c | 11.06 ± 0.49c3 |
AST (U/L) | 133.47±2.13 | 327.01±1.453 | 175.18 ±7.28c2 | 241.04 ±13.73c3 | 239.78±0.59c3 |
Creatinine (mg/dL) | 1.77 ± 0.15 | 7.86 ± 0.493 | 2.57 ± 0.40c | 0.73 ± 0.28c | 1.71 ± 0.20c |
Each value represents the mean ± SEM (n = 5). NTR: normotensive rats receiving distilled water (10 mL/kg), HTR: hypertensive rats receiving distilled water (10 mL/kg) and ethanol (5 g/kg), L h 100 and L h 200: hypertensive rats receiving ethanol and Leersia hexandra extract at doses of 100 and 200 mg/kg, and Nif. 10: hypertensive rats receiving nifedipine at the dose of 10 mg/kg; 2: p <0.01 and 3: p <0.001: significant difference compared to the normal control; c: p <0.001: significant difference compared to hypertensive rats.