Table 2.
Patient Characteristics for IHC Validation Cohort
| patients | no cancer(%) | cancer(%) | P value |
|---|---|---|---|
| N = 63 | N = 86 | ||
| age ± SD | 66.3 ± 20.9 | 62.9 ± 10.4 | 0.616a |
| gender | 0.381b | ||
| male | 31 (49) | 49 (57) | |
| female | 32 (51) | 37 (43) | |
| race | 0.179b | ||
| Caucasian | 58 (92) | 84 (98) | |
| African American | 3 (5) | 2 (2) | |
| other | 2 (3) | 0 (0) | |
| nodule size (mm) ± SD | 22.0 ± 16.0 | 30.0 ± 20.0 | 0.014a |
| smoking status | <0.001b | ||
| never smoker | 20 (32) | 6 (7) | |
| ex-smoker | 33 (53) | 55 (63) | |
| current smoker | 10 (16) | 25 (29) | |
| pack years ± SD | 27.0 ± 30.1 | 45.5 ± 31.7 | <0.001a |
| FEV1% ± SD | 67.0 ± 22.5 | 65.3 ± 24.1 | 0.660a |
| lung cancer histologies | |||
| ADC | 41 (48) | ||
| SCC | 31 (36) | ||
| NSCLC | 7 (8) | ||
| LCC | 5 (6) | ||
| carcinoid | 2 (2) | ||
| path stages | |||
| IA-IB | 55 (64) | ||
| IIA-IIIA | 19 (22) | ||
| IIIB-IV | 12 (14) | ||
| benign histologies | |||
| acid fast bacilli | 5 (8) | ||
| acute inflam. | 3 (5) | ||
| benign tumor | 2 (2) | ||
| fungal | 25 (40) | ||
| multiple etiologies | 25 (40) | ||
| normal lung | 3 (5) | ||
a
Wilcoxon Rank Sum Test.
b
Pearson Chi-Square Test.