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. 2019 Jan 14;9:741. doi: 10.3389/fgene.2018.00741

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Copyright © 2019 Nguyen and Xie.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Enrichment of alternative exons downstream of the REPAG 3′ SS among 198 species/lineages. (A) Percentages of species that show highly significant enrichment (p < 0.001) of alternative exons downstream of the REPAG 3′ SS in each division/group (n = 123 unique species in total). (B) Correlation between the species percentages and the fold enrichment of REPAG 3′ SS (over fungal species) in each division/group. (C–G) Representative examples of 3′ SS and alternative exons of protein-coding and non-protein-coding genes of several species. Uppercases are exon and lowercases intron nucleotides. ^∗location of GGG. The 3′ AG is underlined. The branch point (BP) Adenosine A is in bold and uppercase, and position is relative to the intron end G nucleotide (–1).