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. 2019 Jan 14;9:1572. doi: 10.3389/fphar.2018.01572

FIGURE 3.

FIGURE 3

Key mitochondrial oxidative metabolism enzyme levels had no significant change but activities in LPS treated WT mice is significantly reduced. (A) Representative immunoblots of succinate dehydrogenase (SDH-A 70 kDa), citrate synthetase (CS 52 kDa), cytochrome c oxidase IV (COX IV 17 kDa), and loading control prohibitin (32 kDa). Densitometric quantification of (B) CS, (C) SDH-A, (D) COX IV, and (E) CS activity, (F) NADH:ubiquinone oxidoreductase activity, and (G) succinate dehydrogenase activity in hearts from WT and sEH null mice. Data presented as mean ± SEM, N = 5. Statistics: Two-way ANOVA with Tukey’s post hoc test. ∗p < 0.05 vs. control, #p < 0.05 vs. WT LPS treatment groups.