Table 6.
Toll-like receptor genes identified in frog species.
| Family | Subfamily | X. tropicalis | X. laevis | Other frogs |
|---|---|---|---|---|
| TLR2 | TLR1 | tlr1 (186) | tlr1$ (186) | B. maxima$ (183) |
| TLR2 | tlr2.1, tlr2.2 (186) | tlr2$ (186) |
R. japonica$(187) R. ornativentris$ (187) R. tagoi tagoi$ (187) B. maxima$ (183) |
|
| TLR6 | tlr6.1, tlr6.2 (186) | tlr6$ (186) | B. maxima$ (183) | |
| TLR10 | Not identified (184, 186) | |||
| TLR14 and TLR14-like | tlr14.1, tlr14.2, tlr14.3, tlr14.4 (184, 186) | tlr14$ (186) | ||
| TLR3 | TLR3 | tlr3 (184, 186) | tlr3$ (186) | B. maxima$ (183) |
| TLR4 | TLR4 |
tlr4 (184) tlr4 found in non-coding region (186) |
tlr4$ (186) |
R. japonica$(187) R. ornativentris$ (187) R. tagoi tagoi$ (187) B. maxima$ (183) |
| TLR5 | TLR5 | tlr5 (184, 186), tlrs5* (184) | tlr5$ (184, 186) | B. maxima$ (183) |
| TLR7 | TLR7 | tlr7 (184, 186) | tlr7$ (186) | B. maxima$ (183) |
| TLR8 | tlr8.1, tlr8.2 (186) | tlr8$ (186) | B. maxima$ (183) | |
| TLR9 | tlr9 (184, 186) | tlr9$ (186) | ||
| TLR12 | TLR12 | tlr12 (186) | tlr12$ (186) | |
| TLR13 | tlr13 (184, 186) | tlr13$ (186) | ||
| TLR21 | tlr21 (184, 186) | tlr21$ (186) | ||
| TLR22 | tlr22 (184, 186) | tlr22$ (186) |
X. tropicalis tlr genes shown in bold are predicted to contain introns, non-bolded genes are predicted to be intronless.
*
Soluble short form lacks the transmembrane and TIR domains.
$
Sequences were detected by RT-PCR with cDNA as a template, gene sequence structure not reported.