Table 2.
Longitudinal Developmental Trajectories: Model Parameters and Predicted Valuesa
| Parameter | Values for GMFCS Level: | ||||
|---|---|---|---|---|---|
| I | II | III | IV | V | |
| Fitted model | 1 | 1 | 2 | 3 | 3 |
| No. of children | 227 | 161 | 80 | 129 | 111 |
| No. of observations | 874 | 611 | 298 | 487 | 443 |
| Mean no. of observations/child | 3.9 | 3.8 | 3.7 | 3.8 | 4.0 |
| Fixed effects | |||||
| Limit | 98.3 | 90.6 | 50.6 | 25.30 | 6.46 |
| 95% CI | 97.7–98.7 | 86.3–93.6 | 45.8–55.4 | 23.3–27.4 | 5.5–7.6 |
| Time-90 (mo) | 34.6 | 71.0 | 70.7 | 45.0 | 33.7 |
| 95% CI | 27.8–43.0 | 54.8–92.1 | 54.1–92.3 | 34.4–58.9 | 15.0–75.6 |
| Outcome at ageb | 94.5 | 73.0 | |||
| 95% CI | 93.2–95.5 | 70.8–75.1 | |||
| Random effects | |||||
| Residual SD | 3.9 | 16.7 | 6.0 | 3.76 | 2.94 |
| 50% range | |||||
| Limit | 96.6–99.2 | 90.6–90.6c | 40.4–60.8 | 19.0–32.9 | 3.9–10.5 |
| Time-90 (mo) | 19.5–61.3 | 71.0–71.0c | 21.3–21.3 | 45.0–45.0 | Not estimated |
| Outcome at ageb | 90.7–96.8 | Not estimated | |||
| Population predicted mean (95% CI) for ECAB score | |||||
| 2 y | 54.1 (27.4–71.6) | 34.2 (27.9–39.6) | 27.4 (24.5–30.5) | 17.8 (16.0–19.7) | 5.1 (3.8–6.2) |
| 5 y | 94.5 (93.4–95.4) | 73.0 (71.3–74.7) | 43.3 (40.8–45.9) | 24.1 (22.6–25.6) | 6.3 (5.5–7.1) |
| 12 y | 98.3 (97.8–98.6) | 89.1 (86.6–91.1) | 50.1 (46.5–53.6) | 25.3 (23.7–27.0) | 6.5 (5.7–7.4) |
| Change from 2 to 5 y | 40.4 (23.2–66.7) | 38.8 (32.7–45.5) | 15.9 (13.6–17.7) | 6.2 (4.8–7.6) | 1.2 (0.3–2.1) |
| Change from 5 to 12 y | 3.8 (2.9–4.9) | 16.2 (12.5–19.1) | 6.8 (4.0–9.9) | 1.2 (0.5–2.2) | 0.2 (0.0–0.8) |
a
Definitions of fixed and random effects are provided in the statistical supplement (available at https://academic.oup.com/ptj). ECAB = Early Clinical Assessment of Balance; GMFCS = Gross Motor Function Classification System.
b
Centering age.
c
Negligible random effects for this parameter.