TABLE 2.
Subject | Age (yrs) | Sex | Race | Disease | Donor | HLA matchb | Engraftment dayd ,e | GVHD dayd ,f |
---|---|---|---|---|---|---|---|---|
Case 1 | 46 | Male | Caucasian | AML | Unrelated | Mismatchedc | 17 | |
Control 1 | 56 | Male | Hispanic | AML | Unrelated | Mismatchedc | 8 | 47 |
Case 2 | 59 | Male | Caucasian | NHL | Related | Matched | 15 | 27 |
Control 2 | 64 | Male | Caucasian | MDS | Unrelated | Matched | 27 | 49 |
Case 3 | 54 | Female | Caucasian | MM | Unrelated | Matched | 21 | 30 |
Control 3 | 57 | Female | Caucasian | NHL | Unrelated | Matched | 21 | |
Case 4 | 53 | Female | Caucasian | MM | Related | Matched | 13 | |
Control 4 | 57 | Female | Caucasian | MDS | Related | Matched | 20 | |
Case 5 | 61 | Male | Caucasian | MM | Self | Matched | 16 | |
Control 5 | 72 | Male | Caucasian | MM | Self | Matched | 16 | |
Case 6 | 44 | Male | Caucasian | HD | Unrelated | Matched | 12 | 28 |
Case 7 | 54 | Female | Caucasian | AML | Unrelated | Mismatchedc | 20 | 39 |
HLA, human leukocyte antigen; GVHD, graft-versus-host disease; AML, acute myelogenous leukemia; NHL, non-Hodgkin’s lymphoma; MDS, myelodysplastic syndrome; MM, multiple myeloma; HD, Hodgkin’s disease.
“Matched” indicates 10/10 allele or antigen matching.
Umbilical cord blood was used as the source of donor cells.
Number of days post-HCT.
Engraftment was defined as the first of three consecutive days of an absolute neutrophil count of >500 cells/µl.
GVHD was defined as previously described in reference 37.