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. 2019 Jan 9;9(1):e023139. doi: 10.1136/bmjopen-2018-023139

Table 2.

Contraindications and adverse events relating to NIV therapy

Absolute contraindications Relative contraindications Major adverse event Transient physiological event
Cardiac or respiratory arrest Mildly decreased level of consciousness Anastomotic leak Hypotension, defined as a decrease in blood pressure >20 mm Hg determined by pre/post blood pressure observations
Severe agitation or encephalopathy Progressive severe respiratory failure as reported by the treating physician Severe hypotension requiring increase in medical management Decrease in SpO2 oxygen saturations >10% from baseline or<85% for >60 s
Undrained pneumothorax or intraoperative pneumothorax with ICC in situ Uncooperative patient who can be calmed or comforted Cardiac or respiratory arrest Gastric distention as clinically reported by the treating surgeon
Uncontrolled vomiting SpO2 falls below >10% below resting level of <85% for >60 s Deterioration in medical condition requiring an increase in medical management Vomiting during the NIV therapy
Inability to protect airway MAP<target pressure despite vasopressor Nasal bridge or facial erythema or ulceration
Severe upper GI bleeding or haemoptysis Resting HR <50 or >140 or new untreated arrhythmia develops
Need for immediate intubation RR <5 or >40 b/min
Facial trauma

HR, heart rate; ICC, intercostal catheter; MAP, mean arterial pressure; NIV, non-invasive ventilation; RR, respiratory rate; SpO2, saturation of peripheral oxygen; upper GI, upper gastrointestinal.