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. 2019 Jan 14;8:657. doi: 10.3389/fonc.2018.00657

Table 3.

Associations between SNPs and NHL risk.

Gene SNP Minor allele Alternative allele UNAFF Counta AFF Countb OR (95% CI) c Pca_BHd Pm_BHe
IL-10 rs1518111 G A 52/193/150 15/89/58 1.18 (0.78, 1.79) 0.78 0.65
IL-10 rs3021094 G T 72/208/103 24/90/41 0.77 (0.49, 1.19) 0.73 0.48
IL-10 rs1800893 T C 5/125/260 3/90/68 2.84 (1.66, 4.95) 3.00E-06 0.002
CYP1B1 rs1056836 G C 8/109/267 1/41/113 0.74 (0.39, 1.34) 0.62 0.55
IL-1RN rs4251961 C T 4/73/311 7/46/109 2.54 (1.43, 4.58) 0.002 0.007
OGG1 rs1052133 G C 89/186/123 31/99/32 1.11 (0.74, 1.69) 0.49 0.79
OGG1 rs293795 G A 1/30/386 2/22/145 1.73 (0.85, 3.53) 0.03 0.31
IL-4 rs2243267 C G 14/180/188 6/75/74 1.01 (0.61, 1.66) 0.78 0.98
TNF rs1041981 T G 72/207/105 32/93/30 1.34 (0.88, 2.05) 0.32 0.39
TNF rs1800630 T G 16/101/270 2/77/83 2.35 (1.4, 3.98) 0.01 0.007
TNF rs1800629 A G 2/61/319 1/20/134 0.37 (0.17, 0.76) 0.73 0.03
PON1 rs3917567 C T 4/74/317 4/29/129 1.06 (0.57, 1.96) 0.73 0.89
PON1 rs662 A G 51/191/142 20/74/61 0.68 (0.44, 1.03) 0.73 0.20
PON1 rs13306698 C T 0/18/379 0/46/116 10.82 (4.34, 28.88) 2.01E-14 2.00E-05
PON1 rs854560 T A 2/26/356 0/15/140 0.84 (0.3, 2.23) 0.73 0.89
NAT2 rs1799931 A G 6/90/288 1/22/139 0.27 (0.13, 0.54) 0.02 0.003
CYP2E1 rs743534 C A 12/109/262 2/37/116 0.82 (0.45, 1.48) 0.30 0.72
CYP2E1 rs2480258 C T 104/166/129 44/57/64 0.97 (0.69, 1.36) 0.73 0.89
RAG1 rs3740955 A G 16/141/255 8/67/92 1.55 (0.97, 2.48) 0.35 0.20
ERCC5 rs17655 C G 89/191/104 40/74/41 1.22 (0.82, 1.82) 0.73 0.55
NQO1 rs1800566 T C 80/197/107 39/72/44 1.21 (0.81, 1.8) 0.73 0.55
BRCA1 rs1799966 G A 45/194/156 14/95/53 0.95 (0.6, 1.49) 0.73 0.89
a

UNAFF is the count of genotypes (rare homozygosity/ heterozygosity /common homozygosity) in controls;

b

AFF is the count of genotypes in cases.

c

OR, odds ratio; 95% CI, 95% confidence interval.

d

Pca_BH is the p-value of Cochran-Armitage trend test adjusted by BH method.

e

Pm_BH is the p-value adjusted by BH method using multivariable logistic model adjusted for age, gender, education, family history of cancer and BMI. Bolded variables are statistically significant adjusted by BH method in either univariate or multiple logistic analysis.