Table 4.
Interaction analysis between the environmental risk score variable and each SNP.
| SNP | ROR (95% CI) a | Pb | PBHc | ROR*(95% CI*) d | P*e | PBH*f |
|---|---|---|---|---|---|---|
| rs1518111 | 1.39 (0.7, 2.76) | 0.35 | 0.91 | 2.83 (0.97, 8.28) | 0.06 | 0.64 |
| rs3021094 | 1.18 (0.58, 2.4) | 0.64 | 0.91 | 0.7 (0.21, 2.28) | 0.55 | 0.87 |
| rs1800893 | 1.29 (0.54, 3.06) | 0.56 | 0.91 | 2.96 (0.82, 10.64) | 0.10 | 0.70 |
| rs1056836 | 1.32 (0.5, 3.46) | 0.57 | 0.91 | 0.84 (0.19, 3.72) | 0.81 | 0.87 |
| rs4251961 | 0.95 (0.35, 2.57) | 0.92 | 0.96 | 1.39 (0.3, 6.46) | 0.68 | 0.87 |
| rs1052133 | 1.4 (0.74, 2.64) | 0.30 | 0.91 | 1.56 (0.56, 4.34) | 0.39 | 0.87 |
| rs293795 | 1.37 (0.38, 4.94) | 0.63 | 0.91 | 0.48 (0.07, 3.16) | 0.45 | 0.87 |
| rs2243267 | 1.18 (0.54, 2.58) | 0.68 | 0.91 | 1.6 (0.45, 5.7) | 0.47 | 0.87 |
| rs1041981 | 1 (0.5, 2.01) | 0.99 | 0.99 | 0.77 (0.25, 2.37) | 0.64 | 0.87 |
| rs1800630 | 0.63 (0.27, 1.49) | 0.29 | 0.91 | 1.13 (0.26, 4.87) | 0.87 | 0.87 |
| rs1800629 | 1.68 (0.49, 5.71) | 0.41 | 0.91 | 1.66 (0.25, 11.06) | 0.60 | 0.87 |
| rs3917567 | 0.49 (0.18, 1.39) | 0.18 | 0.91 | 0.56 (0.11, 2.95) | 0.49 | 0.87 |
| rs662 | 1.29 (0.66, 2.54) | 0.46 | 0.91 | 1.6 (0.56, 4.63) | 0.38 | 0.87 |
| rs13306698 | 0.75 (0.14, 3.99) | 0.73 | 0.91 | 0.54 (0.02, 18.05) | 0.73 | 0.87 |
| rs854560 | 4.61 (0.85, 24.93) | 0.08 | 0.91 | 3.56 (0.19, 67.4) | 0.40 | 0.87 |
| rs1799931 | 0.54 (0.18, 1.63) | 0.27 | 0.91 | 0.06 (0.01, 0.44) | 0.006 | 0.12 |
| rs743534 | 0.45 (0.18, 1.13) | 0.09 | 0.91 | 0.55 (0.12, 2.52) | 0.44 | 0.87 |
| rs2480258 | 1.5 (0.84, 2.71) | 0.17 | 0.91 | 0.91 (0.37, 2.26) | 0.84 | 0.87 |
| rs3740955 | 1.19 (0.59, 2.4) | 0.62 | 0.91 | 1.99 (0.67, 5.89) | 0.21 | 0.87 |
| rs17655 | 0.9 (0.46, 1.76) | 0.76 | 0.91 | 0.7 (0.23, 2.13) | 0.53 | 0.87 |
| rs1800566 | 1.05 (0.54, 2.02) | 0.89 | 0.96 | 0.57 (0.19, 1.67) | 0.31 | 0.87 |
| rs1799966 | 1.1 (0.54, 2.25) | 0.79 | 0.91 | 0.85 (0.26, 2.83) | 0.79 | 0.87 |
a
ROR, rate of odds ratio; 95% CI, 95% confidence interval.
b
P, p-value of interaction analysis between ERS and SNP.
c
PBH is the p-value adjusted by BH method.
d
ROR*, rate of odds ratio after adjusting age, gender, education, family history of cancer and BMI; 95% CI*, 95% confidence interval after adjusting age, gender, education, family history of cancer and BMI.
e
P*, p-value of interactive term using multivariable logistic model with adjusting age, gender, education, family history of cancer and BMI.
f
PBH* is the p* value adjusted by BH method.