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Binding of adipic acid linked neoglycoconjugates 20a, 20b, 20d, 21b, and 21c to wild-type 2G12 (top) and to the 2G12-I19R mutant (bottom) as determined by ELISA. Plates were coated with equal amounts of gp140 and neoglycoconjugates. This experiment has been performed twice with similar results.
