Table 3.
Factor | Subgroup | Index | Allele | Carrier | Homozygote | Heterozygote | Dominant | Recessive |
---|---|---|---|---|---|---|---|---|
Race | Asian | OR (95% CIs) | 1.00 (0.89~1.12) | 0.98 (0.86~1.11) | 1.29 (0.94~1.76) | 0.90 (0.78~1.04) | 0.94 (0.82~1.08) | 1.35 (0.99~1.83) |
P a | 0.948 | 0.716 | 0.114 | 0.139 | 0.361 | 0.058 | ||
Case/control | 1696/2139 | 1696/2139 | 1696/2139 | 1696/2139 | 1696/2139 | 1696/2139 | ||
Study number | 10 | 10 | 10 | 10 | 10 | 10 | ||
Race | Caucasian | OR (95% CIs) | 0.98 (0.93~1.03) | 0.98 (0.82~1.04) | 1.00 (0.89~1.12) | 0.94 (0.87~1.01) | 0.95 (0.89~1.02) | 1.02 (0.91~1.14) |
P a | 0.358 | 0.447 | 0.984 | 0.099 | 0.153 | 0.716 | ||
Case/control | 5968/9719 | 5968/9719 | 5968/9719 | 5968/9719 | 5968/9719 | 5968/9719 | ||
Study number | 30 | 30 | 30 | 30 | 30 | 30 | ||
genotyping assay | PCR-RFLP | OR (95% CIs) | 0.99 (0.94~1.03) | 0.99 (0.93~1.04) | 1.01 (0.91~1.12) | 0.96 (0.90~1.03) | 0.97 (0.91~1.03) | 1.01 (0.91~1.12) |
P a | 0.542 | 0.579 | 0.874 | 0.260 | 0.351 | 0.824 | ||
Case/control | 8008/11,342 | 8008/11,342 | 8008/11,342 | 8008/11,342 | 8008/11,342 | 8008/11,342 | ||
Study number | 42 | 42 | 42 | 42 | 42 | 42 | ||
control source | PB | OR (95% CIs) | 0.98 (0.94~1.03) | 0.98 (0.93~1.04) | 1.00 (0.90~1.12) | 0.96 (0.89~1.03) | 0.96 (0.90~1.03) | 1.02 (0.92~1.13) |
P a | 0.519 | 0.572 | 0.943 | 0.214 | 0.287 | 0.751 | ||
Case/control | 6697/10,170 | 6697/10,170 | 6697/10,170 | 6697/10,170 | 6697/10,170 | 6697/10,170 | ||
Study number | 31 | 31 | 31 | 31 | 31 | 31 | ||
control source | HB | OR (95% CIs) | 0.98 (0.91~1.06) | 0.98 (0.90~1.07) | 1.00 (0.84~1.20) | 0.95 (0.86~1.06) | 0.96 (0.87~1.07) | 1.01 (0.85~1.19) |
P a | 0.586 | 0.638 | 0.977 | 0.377 | 0.461 | 0.944 | ||
Case/control | 2771/3946 | 2771/3946 | 2771/3946 | 2771/3946 | 2771/3946 | 2771/3946 | ||
Study number | 19 | 19 | 19 | 19 | 19 | 19 |
Pa, P value of association test
PCR-RFLP polymerase chain reaction-restriction fragment length polymorphism, PB population-based, HB hospital-based, OR odds ratio, CIs confidence intervals