Skip to main content
. 2018 Dec 7;4(6):e292. doi: 10.1212/NXG.0000000000000292

Figure 3. MRI findings in patients with ADLD with duplication and those with deletion upstream of LMNB1.

Figure 3

(A) Findings of MRI with T1WI (left panel), FLAIR (middle panel), and DWI (right panel) of patient 1 with LMNB1 duplication at the age of 56 years. Arrows point to the MCP lesion. (B) Findings of MRI with T1WI (left panel), FLAIR (middle panel), and DWI (right panel) of patient 5 with the upstream deletion of LMNB1 at the age of 50 years. ADLD = adult-onset demyelinating leukodystrophy; DWI = diffusion-weighted imaging; FLAIR = fluid-attenuated inversion recovery; MCP = middle cerebellar peduncle; LMNB1 = lamin B1.