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Current TET–ETS fusion pairings identified in Ewing sarcoma
| Translocation | Fusion | Frequency in ESFT |
|---|---|---|
| t(11;22)(q24;q12) | EWSR1–FLI1 | ~85%–90% of cases |
| t(21;22)(q22;q12) | EWSR1–ERG | ~10% of cases |
| t(7;22)(p22;q12) | EWSR1–ETV1 | Rare |
| t(17;22)(q12;q12) | EWSR1–ETV4 | Rare |
| t(2;22)(q35;q12) | EWSR1–FEV | Rare |
| t(16;21)(p11;q22) | FUS–ERG | Rare |
| t(2;16)(q35;p11) | FUS–FEV | Rare |
Abbreviation: ESFT, Ewing sarcoma family of tumors.
