Table 3.
Onset of muscle contractility and MU connectivity reduction
| Post-natal Day | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SOD1(G93A) vs WT |
35 | 42 | 49 | 56 | 63 | 70 | 77 | 84 | 91 | 98 | 105 | 112 | 119 | |
| Twitch | Males | 0.0079→ | ||||||||||||
| Females | - | - | - | - | 0.0427→ | |||||||||
| Tetanic | Males | 0.0119→ | ||||||||||||
| Females | - | - | - | 0.0326→ | ||||||||||
| CMAP | Males | - | 0.04→ | |||||||||||
| Females | - | - | - | - | - | - | - | - | 0.018→ | |||||
| SMUP | Males | - | - | - | - | 0.0244→ | ||||||||
| Females | - | - | - | - | 0.0244→ | |||||||||
| MUNE | Males | - | - | 0.0382→ | ||||||||||
| Females | - | - | - | - | - | - | 0.0157→ | |||||||
Abbreviations: wildtype (WT), compound muscle action potential (CMAP), single motor unit potential (SMUP), motor unit number estimation (MUNE). Dashes represent no significant difference, arrows indicate that difference was significant for duration of study.