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. Author manuscript; available in PMC: 2020 Jan 21.
Published in final edited form as: Chem Soc Rev. 2019 Jan 21;48(2):415–427. doi: 10.1039/c7cs00748e

Figure 10.

Figure 10.

Schematic diagram showing the design of charge switchable NPs for delivery of vancomycin to bacterial cells. b) Zeta potential of NPs, ZP of PLGA-PLH-PEG increases with decreasing pH. c) Minimum inhibitory concentrations (MICs) of vancomycin against S. aureus in different conditions. Significant loss of drug activity observed in PLGA-PEG (Vanco) and free Vanco. Reproduced from reference 46 with permission from American Chemical Society, Copyright © 2012.