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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: DNA Repair (Amst). 2018 Aug 23;71:43–55. doi: 10.1016/j.dnarep.2018.08.006

Figure 3.

Figure 3.

The structures of Pol II EC stalled at intrastrand crosslinks. a, CPD lesion-induced Pol II stall complex (PDB IDs: 2JA6, 4A93 and 2JA7). b, 1,2-dGpG cisplatin DNA lesion-induced Pol II stall complex (PDB ID: 2R7Z). RNA, template strand, non-template strand, and the bridge helix motif of RNA Pol II (Rpb1 810–840) are shown in red, blue, cyan, and green, respectively. The DNA lesion are highlighted and labeled in yellow. The template registers are also marked in the figure. The Pol II active site is indicated in dashed circle.