Seven days after unilateral transection of the sciatic nerve, myelin in the distal nerve segment was stained with luxol fast blue. (a) Ipsilateral nerves from wild type and Ccr2 knockout mice retained about 20% of the myelin reactivity seen in contralateral control nerves. On the other hand, the ipsilateral distal nerves from Wlds mice retained about 80% of the myelin seen in contralateral controls. Micrographs from sections of the ipsilateral (e-g) and contralateral (b-d) from wild type (WT) (b,e), Wlds (c,f) and Ccr2 knockout (d,g). *p<0.05, **p<0.001. Scale bar, 20 µm. From Niemi et al., 2013.