Table 2. Kind, number and the route of suspected drugs as the etiology.
| Etiology | DRESS (n = 7) | SJS (n = 36) | TEN (n = 4) | Total (n = 47) | ||
|---|---|---|---|---|---|---|
| Antibiotics | 3 (42.9) | 15 (41.7) | 3 (75.0) | 21 (44.7) | ||
| Penicillin | 9 | 2 | 11 | |||
| Amoxicillin/clavulate | 7 | 1 | 8 | |||
| TMP/SMX | 2 | 1 | 3 | |||
| Cephalosporine | 2 | 3 | 1 | 6 | ||
| Macrolide | 2 | 2 | ||||
| Dapsone | 1 | 1 | ||||
| Doxycycline | 1 | 1 | ||||
| Antiepileptics | 4 (57.1) | 5 (13.9) | 9 (19.1) | |||
| Phenobarbital | 1 | 1 | 2 | |||
| Carbamazepine | 1 | 2 | 3 | |||
| Lamotrigine | 2 | 2 | 4 | |||
| NSAIDS | 3 (8.3) | 3 (6.4) | ||||
| Acetaminophen | 6 (16.7) | 6 (12.8) | ||||
| Other drugs | 5 (13.9) | 1 (25.0) | 6 (12.8) | |||
| Deflazacort | 1 | 1 | 2 | |||
| Potassium clavulanate | 1 | 1 | ||||
| Guaifenesin | 1 | 1 | ||||
| Streptokinase | 1 | 1 | ||||
| Dacarbazine | 1 | 1 | ||||
| Unknown | 2 | 2 (4.3) | ||||
| Medication numbers | ||||||
| 1 | 4 (57.1) | 21 (58.3) | 2 (50.0) | 27 (57.4) | ||
| ≥2 | 3 (42.9) | 15 (41.7) | 2 (50.0) | 20 (42.6) | ||
| Administration route | ||||||
| Oral | 5 (71.4) | 34 (94.4) | 4 (100) | 43 (91.5) | ||
| IV | 1 (14.3) | 1 (2.1) | ||||
| Unknown route | 1 (14.3) | 2 (5.6) | 3 (6.4) | |||
Values are presented as number (%).
DRESS, drug reaction with eosinophilia and systemic symptoms; SJS, Stevens-Johnson syndrome; TEN, toxic epidermal necrolysis; TMP/SMX, trimethoprim/sulfamethoxazole; NSAIDS, nonsteroidal anti-inflammatory drugs; IV, intravenous.