Table 3. Distance measures for CRPC (N = 13) and CSPC (N = 6) patients.

Distance Measure	CSPC median (range)	CRPC median (range)	p-value
Distance (mm) between SUVmax	3.80 (1.94-11.7)	8.91 (0-60.3)	0.001
distance (mm) between 80%-SUVmax ROI centroids	2.45 (1.1-5.2)	6.56 (1.0-29.7)	0.002
average pairwise distance (mm) between 80%-SUVmax ROIs	4.2 (2.3-10.3)	10.4 (2.8-37.6)	<0.001

Significance was evaluated by permutation test accounting for intra-patient correlations.