Table 2.
Clinical and histopathological characteristics for the entire population.
| Variables | N (%) | Univariate analysis | |
|---|---|---|---|
| 5-year OS (%) | P-value | ||
| Age, years | < 0.001 | ||
| ≤ 65 | 26,305 (46.4) | 85.3 | |
| > 65 | 30,442 (53.6) | 72.6 | |
| Gender | 0.353 | ||
| Male | 27,507 (48.5) | 78.5 | |
| Female | 29,240 (51.5) | 78.7 | |
| Tumor location | 0.763 | ||
| Rectum | 10,613 (18.7) | 78.3 | |
| Colon | 46,134 (81.3) | 78.5 | |
| Histologic grade | < 0.001 | ||
| Well differentiated | 5,382 (9.5) | 87.6 | |
| Moderately differentiated | 41,004 (72.3) | 80.2 | |
| Poorly differentiated | 9,609 (16.9) | 66.9 | |
| Undifferentiated | 752 (1.3) | 65.4 | |
| Tumor size, cm | < 0.001 | ||
| ≤ 5 | 35,672 (62.9) | 80.6 | |
| > 5 | 16,259 (28.7) | 72.2 | |
| Unknown | 4,816 (8.5) | 85.6 | |
| AJCC 8th T stage | < 0.001 | ||
| pT1 | 8,022 (14.1) | 95.5 | |
| pT2 | 9,957 (17.5) | 91.6 | |
| pT3 | 32,726 (57.7) | 75.7 | |
| pT4 | 6,042 (10.7) | 51.6 | |
| NDLN | < 0.001 | ||
| Inadequate (n < 12) | 16,699 (29.4) | 76.2 | |
| Adequate (n ≥ 12) | 40,048 (70.6) | 79.7 | |
N, number; OS, overall survival rate; NDLN, the number of dissected lymph nodes; AJCC, American Joint Committee on Cancer.