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. 2019 Jan 18;39(1):BSR20181277. doi: 10.1042/BSR20181277

Figure 2. TRIM59 knockdown induces apoptosis and regulates apoptosis-related proteins in neuroblastoma cells.

Figure 2

(A) TRIM59 knockdown induces apoptosis in SH-SY5Y (left panel) and SK-N-SH (right panel) cells. (B) Western blot was used to detect expression of some apoptosis-related proteins, including Bax, Bim, Survivin, β-catenin, and c-myc. WT: wide type cells; NC: cells transfected with shNC lentivirus; shTRIM59-1: cells transfected with shTRIM59-1 lentivirus; shTRIM59-2: cells transfected with shTRIM59-2 lentivirus (***P<0.001 vs NC).