Table 4. Stratification analysis by gender for PDLIM4 polymorphisms and osteoporotic fractures risk.
SNP | Case (n=540) | Control (n=540) | P value | Adjusted OR (95% CI) |
---|---|---|---|---|
rs77584624 | ||||
Male | ||||
TT | 219 (40.56%) | 229 (42.41%) | 1.00 (reference) | |
TG/GG | 66 (12.22%) | 62 (11.48%) | 0.66 | 1.055 (0.85–1.28) |
Female | ||||
TT | 196 (36.30%) | 195 (36.11%) | 1.00 (reference) | |
TG/GG | 59 (10.93%) | 54 (10.00%) | 0.78 | 1.042 (0.83–1.27) |
rs78418541 | ||||
Male | ||||
CC | 200 (37.04%) | 216 (40.00%) | 1.00 (reference) | |
CT/TT | 85 (15.74%) | 75 (13.89%) | 0.32 | 1.105 (0.91–1.32) |
Female | ||||
CC | 203 (37.59%) | 204 (37.78%) | 1.00 (reference) | |
CT/TT | 52 (9.63%) | 45 (8.33%) | 0.58 | 1.075 (0.85–1.32) |
rs270611 | ||||
Male | ||||
CC | 129 (23.89%) | 169 (31.30%) | 1.00 (reference) | |
CA/AA | 156 (28.89%) | 122 (22.59%) | 0.00 | 1.296 (1.09–1.54) |
Female | ||||
CC | 136 (25.19%) | 157 (29.07%) | 1.00 (reference) | |
CA/AA | 119 (22.04%) | 92 (17.04%) | 0.03 | 1.22 (1.01–1.45) |
rs3900945 | ||||
Male | ||||
TT | 123 (22.78%) | 133 (24.63%) | 1.00 (reference) | |
TC/CC | 162 (30.00%) | 158 (29.26%) | 0.60 | 1.054 (0.89–1.26) |
Female | ||||
TT | 112 (20.74%) | 114 (21.11%) | 1.00 (reference) | |
TC/CC | 143 (26.48%) | 135 (25.00%) | 0.74 | 1.038 (0.87–1.25) |
rs366512 | ||||
Male | ||||
CC | 199 (36.85%) | 187 (34.63%) | 1.00 (reference) | |
CT/TT | 86 (15.93%) | 104 (12.96%) | 0.18 | 0.878 (0.72–1.06) |
Female | ||||
CC | 169 (31.30%) | 142 (26.30%) | 1.00 (reference) | |
CT/TT | 86 (15.93%) | 107 (19.81%) | 0.04 | 0.820 (0.67–0.99) |
rs77486529 | ||||
Male | ||||
AA | 218 (40.37%) | 231 (42.78%) | 1.00 (reference) | |
AG/GG | 67 (12.41%) | 60 (11.11%) | 0.46 | 1.087 (0.88–1.31) |
Female | ||||
AA | 203 (37.59%) | 200 (37.04%) | 1.00 (reference) | |
AG/GG | 52 (9.63%) | 49 (9.07%) | 0.93 | 1.022 (0.80–1.26) |
rs71583465 | ||||
Male | ||||
GG | 112 (20.74%) | 121 (22.41%) | 1.00 (reference) | |
GC/CC | 173 (32.04%) | 170 (31.48%) | 0.64 | 1.049 (0.88–1.26) |
Female | ||||
GG | 112 (20.74%) | 117 (21.67%) | 1.00 (reference) | |
GC/CC | 143 (26.48%) | 132 (24.44%) | 0.55 | 1.063 (0.89–1.28) |