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. 2019 Jan 18;39(1):BSR20181505. doi: 10.1042/BSR20181505

Table 4. Stratification analysis by gender for PDLIM4 polymorphisms and osteoporotic fractures risk.

SNP Case (n=540) Control (n=540) P value Adjusted OR (95% CI)
rs77584624
Male
TT 219 (40.56%) 229 (42.41%) 1.00 (reference)
TG/GG 66 (12.22%) 62 (11.48%) 0.66 1.055 (0.85–1.28)
Female
TT 196 (36.30%) 195 (36.11%) 1.00 (reference)
TG/GG 59 (10.93%) 54 (10.00%) 0.78 1.042 (0.83–1.27)
rs78418541
Male
CC 200 (37.04%) 216 (40.00%) 1.00 (reference)
CT/TT 85 (15.74%) 75 (13.89%) 0.32 1.105 (0.91–1.32)
Female
CC 203 (37.59%) 204 (37.78%) 1.00 (reference)
CT/TT 52 (9.63%) 45 (8.33%) 0.58 1.075 (0.85–1.32)
rs270611
Male
CC 129 (23.89%) 169 (31.30%) 1.00 (reference)
CA/AA 156 (28.89%) 122 (22.59%) 0.00 1.296 (1.09–1.54)
Female
CC 136 (25.19%) 157 (29.07%) 1.00 (reference)
CA/AA 119 (22.04%) 92 (17.04%) 0.03 1.22 (1.01–1.45)
rs3900945
Male
TT 123 (22.78%) 133 (24.63%) 1.00 (reference)
TC/CC 162 (30.00%) 158 (29.26%) 0.60 1.054 (0.89–1.26)
Female
TT 112 (20.74%) 114 (21.11%) 1.00 (reference)
TC/CC 143 (26.48%) 135 (25.00%) 0.74 1.038 (0.87–1.25)
rs366512
Male
CC 199 (36.85%) 187 (34.63%) 1.00 (reference)
CT/TT 86 (15.93%) 104 (12.96%) 0.18 0.878 (0.72–1.06)
Female
CC 169 (31.30%) 142 (26.30%) 1.00 (reference)
CT/TT 86 (15.93%) 107 (19.81%) 0.04 0.820 (0.67–0.99)
rs77486529
Male
AA 218 (40.37%) 231 (42.78%) 1.00 (reference)
AG/GG 67 (12.41%) 60 (11.11%) 0.46 1.087 (0.88–1.31)
Female
AA 203 (37.59%) 200 (37.04%) 1.00 (reference)
AG/GG 52 (9.63%) 49 (9.07%) 0.93 1.022 (0.80–1.26)
rs71583465
Male
GG 112 (20.74%) 121 (22.41%) 1.00 (reference)
GC/CC 173 (32.04%) 170 (31.48%) 0.64 1.049 (0.88–1.26)
Female
GG 112 (20.74%) 117 (21.67%) 1.00 (reference)
GC/CC 143 (26.48%) 132 (24.44%) 0.55 1.063 (0.89–1.28)