Table 5. Stratification analysis by ages for PDLIM4 polymorphisms and osteoporotic fractures risk.
SNP | Case (n=540) | Control (n=540) | P value | Adjusted OR (95% CI) |
---|---|---|---|---|
rs77584624 | ||||
<60 years | ||||
TT | 77 (14.26%) | 39 (7.22%) | 1.00 (reference) | |
TG/GG | 23 (4.26%) | 18 (3.33%) | 0.32 | 0.85 (0.59–1.13) |
≥60 years | ||||
TT | 338 (62.59%) | 385 (71.30%) | 1.00 (reference) | |
TG/GG | 102 (18.89%) | 98 (18.15%) | 0.33 | 1.09 (0.92–1.27) |
rs78418541 | ||||
<60 years | ||||
CC | 79 (14.63%) | 43 (7.96%) | 1.00 (reference) | |
CT/TT | 21 (3.89%) | 14 (2.59%) | 0.75 | 0.93 (0.64–1.23) |
≥60 years | ||||
CC | 324 (60.00%) | 377 (69.81%) | 1.00 (reference) | |
CT/TT | 116 (21.48%) | 106 (19.63%) | 0.14 | 1.131 (0.96–1.31) |
rs270611 | ||||
<60 years | ||||
CC | 50 (9.26%) | 22 (4.07%) | 1.00 (reference) | |
CA/AA | 50 (9.26%) | 35 (6.48%) | 0.23 | 0.847 (0.67–1.10) |
≥60 years | ||||
CC | 215 (39.81%) | 304 (56.30%) | 1.00 (reference) | |
CA/AA | 225 (41.67%) | 179 (33.15%) | <0.001 | 1.34 (1.17–1.54) |
rs3900945 | ||||
<60 years | ||||
TT | 50 (9.26%) | 28 (5.19%) | 1.00 (reference) | |
TC/CC | 50 (9.26%) | 29 (5.37%) | 0.92 | 0.987 (0.77–1.27) |
≥60 years | ||||
TT | 185 (34.26%) | 219 (40.56%) | 1.00 (reference) | |
TC/CC | 255 (47.22%) | 264 (48.89%) | 0.35 | 1.07 (0.93–1.24) |
rs366512 | ||||
<60 years | ||||
CC | 55 (10.19%) | 25 (4.63%) | 1.00 (reference) | |
CT/TT | 45 (8.33%) | 32 (5.93%) | 0.24 | 0.85 (0.66–1.10) |
≥60 years | ||||
CC | 313 (57.96%) | 304 (56.30%) | 1.00 (reference) | |
CT/TT | 127 (23.52%) | 179 (33.15%) | 0.01 | 0.818 (0.70–0.96) |
rs77486529 | ||||
<60 years | ||||
AA | 78 (14.44%) | 38 (7.04%) | 1.00 (reference) | |
AG/GG | 22 (4.07%) | 19 (3.52%) | 0.17 | 0.80 (0.55–1.08) |
≥60 years | ||||
AA | 343 (63.52%) | 393 (72.78%) | 1.00 (reference) | |
AG/GG | 97 (17.96%) | 90 (16.67%) | 0.23 | 1.11 (0.94–1.30) |
rs71583465 | ||||
<60 years | ||||
GG | 43 (7.96%) | 26 (4.81%) | 1.00 (reference) | |
GC/CC | 57 (10.56%) | 31 (5.74%) | 0.88 | 1.039 (0.81–1.35) |
≥60 years | ||||
GG | 181 (33.52%) | 212 (39.26%) | 1.00 (reference) | |
GC/CC | 259 (47.96%) | 271 (50.19%) | 0.44 | 1.06 (0.92–1.23) |