Table 4.
Studies | Participant N (mean age ±SD) | MMSE | Diagnostic criteria for AD | Go/No-Go task typologies | Differences between AD group and CG group | ||
---|---|---|---|---|---|---|---|
Accuracy (No-Go) | Reaction time (Go) | Other indices | |||||
Amieva et al., 2002 | CG = 28 (75.2 ± 6.6) | CG = 27.6 ± 1.8 | NINCDS-ADRDA | Go Trial (red circle), No-Go Trial (blue triangle). Two errors: (1) wrongly remove the hand from starting point; (2) replace the hand or continue the action touching the No-Go stimulus. Four Data: RT latencies (Go Trial), Reaching time, I error score; II error score. | AD = CG | AD>CG | N/D[1] |
Mild AD = 28 (75.8 ± 6.1) | Mild AD = 24.6 ± 1.9 | ||||||
Collette et al., 2007 | CG = 28 (70.6 ± 6.8) [13M;15F] | DRS | NINCDS-ADRDA | Go Trial (red circle), No-Go Trial (blue triangle). Two errors: 1) wrongly remove the hand from starting point; (2) replace the hand or continue the action touching the No-Go stimulus. Four Data: RT latencies (Go Trial), Reaching time, I error score; II error score. | AD = CG | AD>CG | N/D |
AD = 25 (72.5 ± 5.8) [18M;17F] | |||||||
FTD = 13 (65.7 ± 7.5) [5M;8F] | |||||||
Stawarczyk et al., 2012 | Study2 | MMSE > 21 | NINCDS-ADRDA | Two conditions: | AD = CG | AD = CG | N/D |
CG = 16 (76.6 ± 10.6) [7M;9F] | Simple RT task (to a stimulus); | ||||||
MildAD = 16 (75.3 ± 10.3) [7M;9F] | 2) Go/No-Go task (responding as rapid as possible to the previous stimuli but not response to other). Two Data: RT of Go Trials; Accuracy of No-Go Trials (Zimmerman and Fimm, 1994). | ||||||
Rochat et al., 2013 | CG = 30 (72.05 ± 7.5) | CG = 27.87 ± 1.61 | NINCDS-ADRDA | SART: response to a rare target (a number). Three data: (1) number of false alarms (measuring of inhibition); (2) RT of correct responses (measuring processing speed); (3) Coefficient of Variation (measuring attention) (Gay et al., 2008). | AD < CG | AD = CG | CoV: AD>CG |
AD = 30 (72.03 ± 5.9) | AD = 23.27 ± 3.24 |
NIA-AA, National Institute on Aging and Alzheimer's Association.