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. 2019 Jan 15;10:437. doi: 10.3389/fnagi.2018.00437

Table 4.

Some characteristics of the studies that have used the Go/No-Go Task to assess executive dysfunction in patients with Alzheimer's disease.

Studies Participant N (mean age ±SD) MMSE Diagnostic criteria for AD Go/No-Go task typologies Differences between AD group and CG group
Accuracy (No-Go) Reaction time (Go) Other indices
Amieva et al., 2002 CG = 28 (75.2 ± 6.6) CG = 27.6 ± 1.8 NINCDS-ADRDA Go Trial (red circle), No-Go Trial (blue triangle). Two errors: (1) wrongly remove the hand from starting point; (2) replace the hand or continue the action touching the No-Go stimulus. Four Data: RT latencies (Go Trial), Reaching time, I error score; II error score. AD = CG AD>CG N/D[1]
Mild AD = 28 (75.8 ± 6.1) Mild AD = 24.6 ± 1.9
Collette et al., 2007 CG = 28 (70.6 ± 6.8) [13M;15F] DRS NINCDS-ADRDA Go Trial (red circle), No-Go Trial (blue triangle). Two errors: 1) wrongly remove the hand from starting point; (2) replace the hand or continue the action touching the No-Go stimulus. Four Data: RT latencies (Go Trial), Reaching time, I error score; II error score. AD = CG AD>CG N/D
AD = 25 (72.5 ± 5.8) [18M;17F]
FTD = 13 (65.7 ± 7.5) [5M;8F]
Stawarczyk et al., 2012 Study2 MMSE > 21 NINCDS-ADRDA Two conditions: AD = CG AD = CG N/D
CG = 16 (76.6 ± 10.6) [7M;9F] Simple RT task (to a stimulus);
MildAD = 16 (75.3 ± 10.3) [7M;9F] 2) Go/No-Go task (responding as rapid as possible to the previous stimuli but not response to other). Two Data: RT of Go Trials; Accuracy of No-Go Trials (Zimmerman and Fimm, 1994).
Rochat et al., 2013 CG = 30 (72.05 ± 7.5) CG = 27.87 ± 1.61 NINCDS-ADRDA SART: response to a rare target (a number). Three data: (1) number of false alarms (measuring of inhibition); (2) RT of correct responses (measuring processing speed); (3) Coefficient of Variation (measuring attention) (Gay et al., 2008). AD < CG AD = CG CoV: AD>CG
AD = 30 (72.03 ± 5.9) AD = 23.27 ± 3.24

NIA-AA, National Institute on Aging and Alzheimer's Association.