Table 1.
Variability of telomeric repeats.
| Species | Taxonomical classification* | Telomeric repeat (5′ → 3′) | # nt | % [G/C] |
|---|---|---|---|---|
| Homo sapiens | A/M | TTAGGG | 6 | 50/0 |
| Arabidopsis thaliana | P | TTTAGGG | 7 | 43/0 |
| U. maydis | F/B | TTAGGG | 6 | 50/0 |
| N. crassa | F/A/P | TTAGGG | 6 | 50/0 |
| Y. lipolytica | F/A/S | TTAGTCAGGG | 10 | 40/10 |
| Spathaspora passalidarum | F/A/S | TTCGGGGTACTCTCTTATGTTGCGGGTAGGATG | 34 | 35/14 |
| C. albicans | F/A/S | TctAactTctTGgtGTaCGGATG | 23 | 26/17 |
| C. parapsilosis | F/A/S | TtgAttaTacTGagGTcCGGATG | 23 | 30/13 |
| S. cerevisiae | F/A/S | TG2−3(TG)1−6 | 5-16 | (max) 56/0 |
| S. pombe | F/A/T | G2−8TTACAC0−1 | 7-14 | (max) 57/14 |
Representative examples that defy the rule that the telomeric repeat is conserved, short and G-rich are shown (reviewed in Červenák et al., 2017). Small letters in the corresponding sequences indicate variable positions in telomeric repeats of the closely related Candida species such as C. albicans and C. parapsilosis illustrating a rapid evolution of the repeats in yeasts.
*
A/M, Animalia/Mammalia; P, Plantae, F/B, Fungi/Basidiomycota; F/A/P, Fungi/Ascomycota/Pezizomycotina; F/A/S, Fungi/Ascomycota/Saccharomycotina; F/A/T, Fungi/Ascomycota/Taphrinomycotina.