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. 2019 Jan 21;5:4. doi: 10.1038/s41522-018-0077-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Principle coordinates analysis (PCoA) scree plots based on the diversity of key taxa identified by the three strategies (abundance-, prevalence-, and hub-based) for each clinical state (i.e. baseline, unwell, and pulmonary exacerbations). Each PCoA axis is plotted against the total percent variance explained (PVE) on the left y-axis, while the cumulative percent variance explained is plotted in green on the right y-axis. The two dashed lines in each plot correspond to the 50% and 90% cumulative PVE