Fig. 3.

The DNA copy number alteration landscape of mucosal melanomas from human, canine, and equine patients. Shown are genome-wide frequencies of somatic copy number gains and losses in primary a human mucosal, b canine oral, and c equine melanomas from mucosal-like/mucocutaneous and cutaneous sites in 1 Mb windows. The pattern of genome-wide frequencies of SCNAs in canine and human melanomas was similar to those reported previously. For equine cases, frequent gain of chromosome 25 and loss of chromosome 31 was observed in tumors from mucosal-like or mucocutaneous sites. Included were samples that passed manual quality control (Supplementary Data 4), as described in the Methods