Table 1.
Effects of germinated brown rice and synbiotics on DMH/DSS‐induced ACF (number/cm2) according to the various size of crypts in the colon of male F344 ratsa , b
| Group c | Incidence d | ACF with | Small ACF (≦3 ACs) | Large ACF (≧4 ACs) | Total ACF | ||
|---|---|---|---|---|---|---|---|
| 1 AC | 2 ACs | 3 ACs | |||||
| D | 100% (9/9) | 2.2 ± 0.8A | 3.3 ± 0.9 | 1.6 ± 0.5 | 7.0 ± 1.8 | 0.7 ± 0.4 | 7.8 ± 2.1 |
| G | 100% (12/12) | 1.7 ± 0.8A,B | 2.9 ± 1.1 | 1.6 ± 0.7 | 6.1 ± 2.3 | 0.7 ± 0.4 | 6.9 ± 2.6 |
| GA | 100% (12/12) | 1.1 ± 0.6B | 2.6 ± 1.2 | 1.6 ± 1.1 | 5.3 ± 2.6 | 0.8 ± 0.5 | 6.1 ± 2.9 |
| GB | 100% (12/12) | 1.6 ± 0.6A,B | 2.9 ± 0.7 | 1.5 ± 0.4 | 6.0 ± 1.4 | 0.6 ± 0.4 | 6.6 ± 1.5 |
| GAB | 100% (12/12) | 1.6 ± 0.8A,B | 2.9 ± 1.3 | 2.0 ± 0.7 | 6.6 ± 2.4 | 1.0 ± 0.3 | 7.5 ± 2.5 |
aAll values are mean ± SD (n = 9–12). bValues with the same letter in a column are not significantly different from one another as determined by ANOVA and Duncan's multiple range test, p < 0.05. cAll rats were administered with DMH/DSS. D, AIN‐93G diet; G, AIN‐93G containing 10% germinated brown rice; GA, AIN‐93G containing 10% GBR + 5 × 107 c.f.u./g L. acidophilus; GB, AIN‐93G containing 10% GBR + 5 × 107 c.f.u./g B. animalis subsp. lactis; GAB, AIN‐93G containing 10% GBR + 2.5 × 107 c.f.u./g L. acidophilus + 2.5 × 107 c.f.u./g diet B. animalis subsp. lactis. dNumber of rats with ACF/total rats.