Figure 2.

Inhibition of cytochrome P450 isoezymes by herbs with IC₅₀ < 1,000 µg/ml–aqueous extracts of Alstonia boonei (a), Mangifera indica (b), Picralima nitida (c), Gongronema latifolium (d), Bauhinia monandra (e), and Moringa oleifera (f). Data represents IC₅₀ in L/dose and each bar is an average of duplicate experiments performed on two different occasions. DOM–desmethylomeprazole, 5OH, 5‐hydroxyomeprazole; 3OH, 3‐hydroxyomeprazole; OS, omeprazole sulphone; TES, 6β‐hydroxytestosterone; MID, 1‐hydroxymidazolam