Table 3.

Effects of Diet I and Diet II on blood plasma biochemistry in NDEA‐induced hepatocarcinogenesis rats at 20th week

Parameter/Groups	ConD	ConD+NDEA	Diet I+NDEA	Diet II+NDEA
AST(U/L)	65.00 ± 36.33	185.63 ± 61.70**	137.10 ± 4.52**##	99.20 ± 13.50*##
ALT(U/L)	40.70 ± 8.84	107.25 ± 42.48**	40.30 ± 11.76##	35.10 ± 9.48##
GGT(U/L)	1.61 ± 0.24	2.57 ± 0.21**	1.57 ± 0.62##	1.52 ± 0.12##
TBIL(μmol/L)	2.32 ± 0.26	4.20 ± 0.94**	2.24 ± 0.40##	2.30 ± 0.17##
ALP(U/L)	56.60 ± 10.43	85.63 ± 17.11**	62.20 ± 20.82##	53.80 ± 9.37##
Total protein (g/L)	65.75 ± 9.78	65.60 ± 12.25	59.37 ± 9.46	60.43 ± 10.83
Albumin (g/L)	27.04 ± 0.83	29.26 ± 2.11*	25.38 ± 2.50##	26.76 ± 2.12##
Globulin (g/L)	38.71 ± 10.12	36.34 ± 11.43	29.99 ± 9.94	33.67 ± 10.83
AFP(ng/ml)	3.73 ± 0.50	5.84 ± 1.26**	3.25 ± 0.54##	3.53 ± 1.67##
CEA(ng/ml)	1.83 ± 0.34	2.25 ± 0.34**	2.07 ± 0.30	2.08 ± 0.38
TSGF(μg/ml)	23.70 ± 1.34	36.31 ± 7.99**	28.39 ± 5.14##	26.09 ± 4.79##
DKK1(ng/ml)	1.47 ± 0.23	7.83 ± 1.85**	3.61 ± 0.90##	3.20 ± 1.20##

Values are given as mean ± SD, n = 8. Comparisons: compared with ConD group, *p < 0.05; **p < 0.01; compared with ConD+NDEA group,^## p < 0.01 (Student's t test). AFP: alpha fetal protein; ALB: albumin; ALP: alkaline phosphatase; ALT: alanine aminotransferase; AST: aspartate transaminase; CEA: carcinoembryonic antigen; DKK1: dickkopf‐related protein 1; GGT: γ‐glutamyl transpeptidase; GST: glutathione‐S‐transferase; TBIL: total bilirubin; TP: total protein; TSGF: tumor‐specific growth factor.